In arguing that the jury had to find Laura “not guilty by reason of insanity,” Quint and Cook hoped to focus their attention around four central issues. At the heart of their case, they argued, was the notion that Laura was unconscious and irrational at the time of the murder. In contrast to the prosecution, which had relied on gossip and rumor to condemn Laura’s character, they would base their case on the latest scientific findings and medical expertise. By calling to the stand doctors with advanced knowledge and training, they would prove that Laura—much like Mary Harris before her—was a victim herself, captive to the effects of severe organic disease. Especially when her menstrual cycle approached, she experienced recurring bouts of hysterical mania that left her without control of her actions or awareness of events. Thus, no matter how heinous the act appeared, she was not responsible for its commission.